Utilizing Pharmacogenomics When Selecting Personalized Medicine for Patients with Chronic Pain
Agitation refers to a spectrum of abnormal behaviors often seen in patients with various psychiatric illnesses, including those with schizophrenia or bipolar disorder.
Agitation refers to a spectrum of abnormal behaviors frequently seen in patients with psychiatric illnesses, including in individuals with schizophrenia or bipolar disorder. It is a mental and physical state that is characterized by motor restlessness, mental tension, and excitement, and it is often marked by poorly organized, aimless psychomotor activity. Agitated patients may exhibit aggressive behavior, resulting in harm to themselves, other patients, and healthcare workers. Therefore, prompt and effective management of agitation is critically important in the care of schizophrenia or bipolar disorder, and it requires the skills and expertise of several types of professionals. Typically, both pharmacologic and nonpharmacologic strategies are necessary to achieve optimal results.
Prescription opioid abuse is a significant public health concern in the United States, particularly abuse of controlled-release formulations that contain higher opioid content.
Chronic noncancer pain is now considered a global epidemic and a public health problem in the United States, partly owing to its prevalence, underdiagnosis, and undertreatment.
Agitation includes a spectrum of abnormal behavioral manifestations that are frequently observed in individuals with psychiatric illnesses, including those with schizophrenia or bipolar disorder.
Comprehensive asthma management comprises several key components of care, including: (1) the assessment and monitoring of current severity of asthma and the future risk for exacerbations; (2) partnership between the patient and the treatment team; (3) control of environmental factors and comorbid conditions; and (4) pharmacologic therapy.
Chronic pain affects approximately 100 million US adults, and has devastating consequences on quality of life (QoL) and functional status.
Asthma is a prevalent chronic condition that affects 235 million individuals worldwide, including children and adults. In the United States, an estimated 24.6 million people or 8.2% of the US population have asthma, and nearly half of these individuals experience at least 1 asthma exacerbation yearly.
In the past several years, there have been significant changes in the management of asthma in the United States, beginning with the publication of the updated Guidelines for the Diagnosis and Management of Asthma in the Expert Panel Report 3 of the National Asthma Education and Prevention Program (NAEPP) in 2007.
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