Clinical
End-stage renal disease (ESRD), also known as stage 5 kidney disease, is characterized by permanent kidney failure. Currently, more than 678,000 Americans have ESRD, and projections indicate that the population of patients with this disease may exceed 2 million by 2030.
Dialysis Procedures and Health-Related Quality of Life: The Challenge of Creating Evidence-Based Healthcare in End-Stage Renal Disease
Dimitrios A. Pappas, MD, Robert A. Gerber, PharmD, Heather J. Litman, PhD;, David Gruben, PhD, Jamie Geier, PhD, Winnie D. Hua, MS, Connie Chen, PharmD, Youfu Li, MD, MPH, Joel M. Kremer, MD, John S. Andrews, MD, Jeffrey A. Bourret, PharmD
Limited Guidelines and Treatment Success in the Current Standard of Care for Patients with Rheumatoid Arthritis Provide an Opportunity to Inform New Treatment Protocols
Rosacea is a chronic inflammatory skin disorder that primarily affects the convexities of the central face.
There’s Room for Improvement in Rosacea Treatment
J. Douglas Thornton, PharmD, PhD, Nilanjana Dwibedi, PhD, Virginia Scott, PhD, Charles D. Ponte, PharmD, Douglas Ziedonis, MD, Nethra Sambamoorthi, PhD, Usha Sambamoorthi, PhD
Chronic noncancer pain is prevalent among US adults, costs approximately $600 billion annually, and can be especially burdensome for working-age adults because of lost productivity and the negative impact of this condition on a patient’s quality of life.
Addiction Prediction: Preventing Iatrogenic Opioid Dependence
Gabriela Dieguez, FSA, MAAA, Christine Ferro, Maushumi Mavinkurve, MPH, Yuri Sanchez Gonzalez, PhD, Bruce Pyenson, FSA, MAAA
Chronic hepatitis C virus (HCV) infection kills more people than any other infectious disease in the United States, and, as of 2013, mortality associated with this disease has been rising.
Importance of Health Outcomes Research for the Treatment of Hepatitis C Infection
In a new study published in February 2018 in American Health & Drug Benefits, researchers have identified opioid prescription characteristics that may increase the patient’s risk for becoming a chronic user of opioid therapy.
JoAnne Foody, MD, Robin S. Turpin, PhD, Beni A. Tidwell, BS, Debra Lawrence, PhD, Kathy L. Schulman, MS
Gout is a metabolic disorder that causes flares of arthritis in the joints and occurs with the onset of inflammation as a result of excess serum uric acid in the blood (ie, hyperuricemia) and the deposition of crystals in tissue.
The Growing Role of Real-World Evidence in Clinical Decision-Making
A First Step Toward Improving the Complex Approach to Metastatic Prostate Cancer Management
Annlouise R. Assaf, PhD, Andrew G. Bushmakin, MS, Nina Joyce, PhD, Michael J. Louie, MD, MPH, MSc, Michael Flores, MPH, Margaret Moffatt, MPH
Hormone Therapy Remains Effective for Treating Menopausal Symptoms, May Save Overall Costs
Narcolepsy is a chronic neurologic disorder, and because there is no known cure, there is a need for lifelong treatment.
Improved Diagnosis and Treatment of Narcolepsy May Also Help to Reduce the Associated Costs
