Clinical
In the United States, more than 80% of all patients with end-stage renal disease (ESRD) initiate dialysis with hemodialysis, and current reports indicate that this trend has changed little over the past 2 decades.
The Challenge of Maintaining Vascular Access in Patients with End-Stage Renal Disease
Adam C. Powell, PhD, Stephen E. Price, DPT, MBA, Khoa Nguyen, MS, Gary L. Smith, MS, James W. Long, BSBA, Uday U. Deshmukh, MD, MPH
For much of modern history, physicians have made decisions about patient care by consulting their peers and by using rule-based approaches. Specialists have been consulted throughout history and became a necessity in the 1800s, as medicine became more complex.
Standardized Documentation Can Improve Diagnostic Testing Decisions for Patients with Cardiovascular Disease
Nicole D. White, PharmD, CDE, Thomas L. Lenz, PharmD, FACLM, Maryann Z. Skrabal, PharmD, CDE, Jessica J. Skradski, PharmD, Louis Lipari
Cardiovascular disease (CVD) remains the leading cause of death in America, resulting in approximately 610,000 deaths each year. The prevalence of CVD in the United States is increasing.
Influencing Patient Outcomes Through Enhanced Multidisease-Focused Interventions
End-stage renal disease (ESRD), also known as stage 5 kidney disease, is characterized by permanent kidney failure. Currently, more than 678,000 Americans have ESRD, and projections indicate that the population of patients with this disease may exceed 2 million by 2030.
Dialysis Procedures and Health-Related Quality of Life: The Challenge of Creating Evidence-Based Healthcare in End-Stage Renal Disease
Dimitrios A. Pappas, MD, Robert A. Gerber, PharmD, Heather J. Litman, PhD;, David Gruben, PhD, Jamie Geier, PhD, Winnie D. Hua, MS, Connie Chen, PharmD, Youfu Li, MD, MPH, Joel M. Kremer, MD, John S. Andrews, MD, Jeffrey A. Bourret, PharmD
Limited Guidelines and Treatment Success in the Current Standard of Care for Patients with Rheumatoid Arthritis Provide an Opportunity to Inform New Treatment Protocols
Rosacea is a chronic inflammatory skin disorder that primarily affects the convexities of the central face.
There’s Room for Improvement in Rosacea Treatment
J. Douglas Thornton, PharmD, PhD, Nilanjana Dwibedi, PhD, Virginia Scott, PhD, Charles D. Ponte, PharmD, Douglas Ziedonis, MD, Nethra Sambamoorthi, PhD, Usha Sambamoorthi, PhD
Chronic noncancer pain is prevalent among US adults, costs approximately $600 billion annually, and can be especially burdensome for working-age adults because of lost productivity and the negative impact of this condition on a patient’s quality of life.
Addiction Prediction: Preventing Iatrogenic Opioid Dependence
Gabriela Dieguez, FSA, MAAA, Christine Ferro, CHFP, Maushumi Mavinkurve, MPH, Yuri Sanchez Gonzalez, PhD, Bruce S. Pyenson, FSA, MAAA
Chronic hepatitis C virus (HCV) infection kills more people than any other infectious disease in the United States, and, as of 2013, mortality associated with this disease has been rising.
Importance of Health Outcomes Research for the Treatment of Hepatitis C Infection
In a new study published in February 2018 in American Health & Drug Benefits, researchers have identified opioid prescription characteristics that may increase the patient’s risk for becoming a chronic user of opioid therapy.
JoAnne Foody, MD, Robin S. Turpin, PhD, Beni A. Tidwell, BS, Debra Lawrence, PhD, Kathy L. Schulman, MS
Gout is a metabolic disorder that causes flares of arthritis in the joints and occurs with the onset of inflammation as a result of excess serum uric acid in the blood (ie, hyperuricemia) and the deposition of crystals in tissue.
The Growing Role of Real-World Evidence in Clinical Decision-Making
