Conference Correspondent

Conference Correspondent

After 5 years of follow-up, single-agent ibrutinib continues to show durable responses in patients with treatment-naive or relapsed/refractory chronic lymphocytic leukemia/small lymphocytic leukemia, including those with del17p, del11q, or unmutated IGVH.
A definitive diagnosis of systemic lupus erythematosus (SLE) differentiating it from other rheumatic and autoimmune diseases can be challenging, because of a lack of definitive tests with sufficient sensitivity and specificity, as well as the absence of reliable biomarkers.
Systemic lupus erythematosus (SLE) often affects women of childbearing age. Pregnant women with SLE are known to be at increased risk of miscarriage and other complications during pregnancy.
Two important studies presented at the American College of Rheumatology annual meeting held in San Diego, California from October 25-30, 2013 analyzed the prevalence of systemic lupus erythematosus (SLE) and lupus nephritis in the US population, as well as the impact of SLE on employment and work productivity in American workers.
Blisibimod is a subcutaneously administered inhibitor of B-cell activating factor (BAFF) that has been evaluated in patients with systemic lupus erythematosus (SLE) in the phase 2b PEARL-SC trial and in an ensuing open-label extension study (NCT01305746).
Epratuzumab is an anti-CD22 monoclonal antibody that modulates B-cell activation and has demonstrated clinically relevant improvements in disease activity in patients with moderate-to-severe systemic lupus erythematosus (SLE) in the phase 2b EMBLEM study (Wallace DJ, et al. Ann Rheum Dis. 2013 Jan 12. Epub ahead of print)
Patients with systemic lupus erythematosus (SLE) frequently require corticosteroids as standard therapy.
Large-scale phase 3 clinical trials have already demonstrated the clinical efficacy of belimumab (Benlysta) in patients with systemic lupus erythematosus (SLE), which served as the basis for the US Food and Drug Administration approval of this medication for adult patients with active, autoantibody-positive SLE who are receiving standard therapy.
Belimumab (Benlysta) is a human monoclonal antibody that inhibits B-lymphocyte stimulator that is approved by the US Food and Drug Administration for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) who are receiving standard therapy.
Elevation of interferon type I (IFN-I) is associated with more severe disease in patients with systemic lupus erythematosus (SLE), although the relationship between elevated levels of IFN-I and SLE disease activity over time has not been defined.
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  •  Association for Value-Based Cancer Care
  • Value-Based Cancer Care
  • Value-Based Care in Rheumatology
  • Oncology Practice Management
  • Rheumatology Practice Management
  • Urology Practice Management
  • Inside Patient Care: Pharmacy & Clinic
  • National Association of Specialty Pharmacy
  • Lynx CME