Original Research
In the United States, more than 80% of all patients with end-stage renal disease (ESRD) initiate dialysis with hemodialysis, and current reports indicate that this trend has changed little over the past 2 decades.
The Challenge of Maintaining Vascular Access in Patients with End-Stage Renal Disease
Christine Ferro, CHFP, Bruce S. Pyenson, FSA, MAAA, Jocelyn Lau, MPH, Mona Kelkar, MBA, Nancy Phillips, MD, Chi-Wei Lu, PhD, Percy Yeung, PhD, Gloria Bachmann, MD
During the later weeks of pregnancy, pregnant women are often concerned with suspected leakage of amniotic fluid, which, whether preterm or at term, requires evaluation and medical intervention. The rupture of membranes occurs in an estimated 8% to 10% of full-term pregnancies.
Interventions to Reduce Avoidable Pregnancy-Related Emergency Department Visits
Inflammatory bowel disease (IBD) is a chronic, lifelong disorder of the gastrointestinal tract associated with an unpredictable relapsing and remitting disease course. Ulcerative colitis (UC) and Crohn’s disease (CD) are 2 common phenotypes of IBD. Patients with IBD often have considerable symptom burden despite appropriate treatment, and IBD frequently leads to debilitating complications that may require hospitalization, surgery, and/or the escalation of therapy.
Adam C. Powell, PhD, Stephen E. Price, DPT, MBA, Khoa Nguyen, MS, Gary L. Smith, MS, James W. Long, BSBA, Uday U. Deshmukh, MD, MPH
For much of modern history, physicians have made decisions about patient care by consulting their peers and by using rule-based approaches. Specialists have been consulted throughout history and became a necessity in the 1800s, as medicine became more complex.
Standardized Documentation Can Improve Diagnostic Testing Decisions for Patients with Cardiovascular Disease
Nicole D. White, PharmD, CDE, Thomas L. Lenz, PharmD, FACLM, Maryann Z. Skrabal, PharmD, CDE, Jessica J. Skradski, PharmD, Louis Lipari
Cardiovascular disease (CVD) remains the leading cause of death in America, resulting in approximately 610,000 deaths each year. The prevalence of CVD in the United States is increasing.
Influencing Patient Outcomes Through Enhanced Multidisease-Focused Interventions
Machaon M.K. Bonafede, PhD, MPH, Donna McMorrow, BS, Clare Proudfoot, PhD, Shraddha Shinde, MS, MBA, Andreas Kuznik, PhD, Chieh-I Chen, MPH
This retrospective analysis is based on inpatient medical claims, outpatient medical claims, and pharmacy claims from the Truven Health MarketScan Commercial Database. The database includes claims for approximately 35 million employees and their dependents in fee-for-service and managed care health plans.
End-stage renal disease (ESRD), also known as stage 5 kidney disease, is characterized by permanent kidney failure. Currently, more than 678,000 Americans have ESRD, and projections indicate that the population of patients with this disease may exceed 2 million by 2030.
Dialysis Procedures and Health-Related Quality of Life: The Challenge of Creating Evidence-Based Healthcare in End-Stage Renal Disease
Narcolepsy is a chronic, disabling sleep disorder characterized by excessive daytime sleepiness and recurrent periods of sudden, unintentional lapses into sleep during the day. This condition may occur with or without cataplexy, an abrupt and typically bilateral loss of skeletal muscle tone that is often triggered by strong emotion that, when severe, may cause the patient to briefly collapse without losing consciousness.
Accurate Diagnosis of Chronic Diseases Can Reduce Costs and Medical Resource Utilization
Dimitrios A. Pappas, MD, Robert A. Gerber, PharmD, Heather J. Litman, PhD;, David Gruben, PhD, Jamie Geier, PhD, Winnie D. Hua, MS, Connie Chen, PharmD, Youfu Li, MD, MPH, Joel M. Kremer, MD, John S. Andrews, MD, Jeffrey A. Bourret, PharmD
Limited Guidelines and Treatment Success in the Current Standard of Care for Patients with Rheumatoid Arthritis Provide an Opportunity to Inform New Treatment Protocols
Jesse Cambon, MEng, Tristan Cordier, MS, Elizabeth L. Munnich, PhD, MPP, Andrew Renda, MD, Bobby Kapur, MD, MPH, Shkelzen Hoxhaj, MD, MPH, MBA, Meredith Williams, MD, MBA
Narrow network plans offer limited provider choice, but they are attractive to premium-sensitive healthcare consumers, because premiums and out-of-pocket costs are lower than plans with broader provider networks. However, the intended cost-savings for individuals and health
Opportunities to Improve Urgent and Emergent Care Utilization
