San Diego, CA—An analysis of real-world administrative claims data in patients with chronic lymphocytic leukemia (CLL) has highlighted the need for treatments that result in fewer adverse events, according to data presented at ASH 2018.
San Diego, CA—For children and young adults diagnosed with acute lymphoblastic leukemia (ALL), receiving treatment at specialized cancer centers has been associated with improved outcomes versus nonspecialized centers, but this comes at an increased cost, according to data presented at ASH 2018.
San Diego, CA—Analysis of healthcare utilization among Medicare beneficiaries with multiple myeloma suggests that the setting of autologous hematopoietic stem-cell transplantation (HSCT) has a significant impact on provider reimbursement and out-of-pocket expenses for patients, according to data presented at ASH 2018.
San Diego, CA—Real-world data highlight the significant clinical and economic burden associated with venous thromboembolism (VTE) in patients with cancer. The data come from a study of 12,785 patients hospitalized with acute illnesses, of which 2002 patients had cancer. The results were presented at ASH 2018 and showed that 3.9% of patients with cancer experienced a VTE event requiring rehospitalization—the highest proportion of patients among the study population. Moreover, 28.2% of VTE-related readmissions occurred within the first 30 days of initial hospital discharge.
Genomic testing is now standard of care for patients with non–small-cell lung cancer (NSCLC). The 4 identified genomic mutations that are targetable with FDA-approved therapies include EGFR, ALK, ROS1, and BRAF, and other NSCLC-associated genetic mutations are targetable with therapies currently being investigated in clinical trials. More genetic mutations are linked to NSCLC, but there is currently no accepted standard for genomic testing in NSCLC, or the optimal timing of such tests.
Poly (ADP ribose) polymerase (PARP) inhibitors are among the new and improved classes of cancer drugs, but their steep costs have become a critical consideration for patients and clinicians. The results of a recent analysis suggest that PARP inhibitors may be the least cost-effective of available maintenance therapies for advanced ovarian cancer. According to data presented at ASCO 2018, to become cost-neutral with anti-VEGF therapy, PARP inhibitors would require at least a 50% reduction in cost.
Healthcare costs in the United States have spiraled out of control, and polls show that single-payer healthcare is gaining traction. Our Canadian neighbors have had a single-payer system for a long time. A study presented at ASCO 2018 puts exact numbers on what it costs to receive treatment for metastatic colorectal cancer (CRC) in demographically similar populations in Washington State versus British Columbia, geographic areas separated by a line of sand but vastly different in terms of "bang for the buck" in cancer care.
With healthcare premiums on the rise and out-of-pocket costs skyrocketing, almost every person diagnosed with cancer is at risk for being underinsured, but this threat extends beyond a patient's bank balance. Recent research has shown that when patients face extreme financial distress, they have a greater risk for worse outcomes, including mortality. At ASCO 2018, Yousuf Zafar, MD, MHS, Director, Center for Applied Cancer Health Policy, Duke Cancer Institute, Durham, NC, discussed the need to prevent financial toxicity at the patient level by focusing on high-­value interventions.
Allergic rhinitis is a common immune-mediated health condition that affects up to 60 million Americans annually. A chronic, inflammatory disease of the upper airways, allergic rhinitis can significantly affect patients’ quality of life (QOL) and productivity.
Chicago, IL—The issues underlying financial toxicity are undoubtedly complex, but for oncologists looking to help their patients cope, simply noting the cost of treatment from the outset may be the best place to start. As the cost of cancer care continues to rise, greater transparency throughout the process of drug pricing and drug payment needs to become part of the clinical discussion, said Leonard Saltz, MD, Chief, Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York City, at the 2017 ASCO annual meeting.
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