In the News

Hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood, is a major controllable risk factor for coronary heart disease, myocardial infarction, and stroke. The risk for cardiovascular disease (CVD) in individuals with high cholesterol is approximately twice that for people with lower cholesterol.
Multiple myeloma is a cancer of plasma cells in the bone marrow that often leads to bone destruction and bone marrow failure. According to the American Cancer Society, more than 26,800 new cases of multiple myeloma were diagnosed in 2015, and 11,240 deaths were attributed to multiple myeloma in the same year.
More than 29 million people in the United States have diabetes, the seventh leading cause of mortality and a major cause of stroke, heart disease, kidney failure, blindness, and other serious conditions. As the US population ages and the number of higher-risk minority groups grows, the incidence of diabetes is projected to nearly double from approximately 8 cases per 1000 individuals in 2008 to approximately 15 cases per 1000 in 2050.
Colony-stimulating factors (CSFs) are endogenous glycoproteins that regulate the production and the functioning of infection-protective granulocytes and macrophages. Overall, 2 types of recombinant CSF drugs—granulocyte CSF (filgrastim, pegfilgrastim) and granulocyte-macrophage CSF (sargramostim)—have been prescribed for more than 20 years to stimulate neutrophils and macrophages, primarily in patients with cancer who are undergoing treatment with cytotoxic chemotherapy.
Rheumatoid arthritis (RA) is a systemic, inflammatory form of arthritis that results in joint inflammation, pain, swelling, and stiffness. Although new treatment strategies that focus on early diagnosis, aggressive treatment, and consistent monitoring have helped many patients achieve their goals, RA continues to present clinical and economic challenges to patients, physicians, and payers.
Omnigraft (Integra Omnigraft Dermal Regeneration Matrix) has been approved by the FDA to treat patients with diabetes who have certain foot ulcers. The device, which is made of silicone, cow collagen, and shark cartilage, provides an environment for new skin and tissue to regenerate and heal the wound when placed over an ulcer.
Fluad, a trivalent vaccine produced using 3 flu virus strains—2 subtype A and 1 type B—has been approved for the prevention of seasonal influenza in patients aged ≥65 years. The vaccine was approved using the accelerated approval regulatory pathway.
Sugammadex (Bridion) injection has been approved by the US Food and Drug Administration to reverse the effects of neuromuscular-blocking drugs (rocuronium bromide and vecuronium bromide) used during tracheal intubation in adults. This injection may help patients recover from these drugs sooner.
Uridine triacetate (Vistogard) has been approved by the US Food and Drug Administration for emergency treatment of patients who receive an overdose of fluorouracil or capecitabine, or those who develop severe toxicities within 4 days of treatment with either therapy.
The US Food and Drug Administration has approved the oral drug alectinib (Alecensa) for the treatment of patients with metastatic, ALK-positive, non−small-cell lung cancer (NSCLC) who could not tolerate, or whose disease worsened after, receiving therapy with crizotinib (Xalkori).
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