Diagnosis and Treatment of Bipolar Disorders in Adults: A Review of the Evidence on Pharmacologic Treatments
Bipolar disorder is a chronic, relapsing illness characterized by recurrent episodes of manic or depressive symptoms, with intervening periods that are relatively (but not fully) symptom-free.
Bipolar Disorders: Balancing Formulary Management and Clinical Outcomes for a Vulnerable Patient Population
Utilization of Parenteral Anticoagulants and Warfarin: Impact on the Risk of Venous Thromboembolism Recurrence in the Outpatient Setting
Jennifer Cai, MS, MPH, Winghan Jacqueline Kwong, PharmD, PhD, Ronald Preblick, PharmD, MPH, Qiaoyi Zhang, MD, PhD, James T. Kenney, RPh, MBA
Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary embolism (PE). VTE is a chronic disease that is associated with a high risk for recurrence, especially during the initial months of therapy.
Better Compliance with Clinical Guidelines for Venous Thromboembolism Can Improve Patient Outcomes, Reduce Costs
Charles Jia-Haur Hu, DO, Chihyi Lin, DO, Brien Rex Miller, DO, Hanh Nguyen, DO, Quang T. Nguyen, DO, FACP, FACE, FTOS
Type 2 diabetes mellitus is an ongoing medical problem that clinicians deal with on a daily basis. The necessity of treating diabetes adequately is essential because of the many comorbidities and complications associated with uncontrolled diabetes.
Addressing Adherence a Key Challenge in the Management of Patients with Type 2 Diabetes
Evaluation of Dabigatran for Appropriateness of Use and Bleeding Events in a Community Hospital Setting
Anastasia L Armbruster, PharmD, BCPS, Katie S Buehler, PharmD, BCPS, Sun H Min, PharmD, Margaret Riley, PharmD, Michael W Daly, PharmD, MSCI, BCPS
The development of innovative medications is largely a private enterprise that relies chiefly on the investment of pharmaceutical companies in research and development (R&D).
Accurate Prescribing Key to Safe Use of Anticoagulants in Patients with Nonvalvular Atrial Fibrillation
Marco daCosta DiBonaventura, PhD, Ronda Copher, PhD, Enrique Basurto, MSc, Claudio Faria, PharmD, MPH, Rose Lorenzo, BA
Cardiovascular Events and Safety Outcomes Associated with Azithromycin Therapy: A Meta-Analysis of Randomized Controlled Trials
Azithromycin has been used for many years for the treatment of patients with various types of bacterial infections, as well as for the secondary prevention of coronary events. There is a growing concern, however, that azithromycin may be associated with an increased cardiovascular (CV) risk and may lead to CV-related death in high-risk patients.
Cardiovascular Safety of Azithromycin Therapy: Revisiting the Evidence
Impact of Linaclotide Treatment on Work Productivity and Activity Impairment in Adults with Irritable Bowel Syndrome with Constipation: Results from 2 Randomized, Double-Blind, Placebo-Controlled Phase 3 Trials
Jessica L. Buono, MPH, Robyn T. Carson, MPH, Jeffrey M. Johnston, MD, Phil Sarocco, RPh, MSc, Stavros Tourkodimitris, PhD
Irritable bowel syndrome with constipation (IBS-C), a chronic functional gastrointestinal disorder, has been shown to negatively affect work productivity and impair daily activity, resulting in a substantial burden for patients and employers. Linaclotide is a first-in-class guanylate cyclase-C agonist approved for the treatment of adults with IBS-C and chronic idiopathic constipation in the United States.
Patient-Reported Outcomes Matter
Salsalate, an Old, Inexpensive Drug with Potential New Indications: A Review of the Evidence from 3 Recent Studies
Kenneth Anderson, DO, Lance Wehrle, DO, Min Park, DO, Kenneth Nelson, DO, Loida D. Nguyen, PharmD, BCPS, Quang T. Nguyen, DO, FACP, FACE, FTOS
Diabetes is a well-known growing epidemic, but prediabetes is increasing at an even greater rate. Lifestyle changes are effective tools to prevent the progression of prediabetes to diabetes, yet many people are unable to follow such changes. Salsalate has been suggested as a possible treatment for diabetes as early as 1876 and as recently as in a 2013 study.
Considering Salsalate Use in Patients at Risk for Diabetes
Treatment Patterns, Survival, and Healthcare Costs of Patients with Malignant Gliomas in a Large US Commercially Insured Population
Saurabh Ray, PhD, Machaon M. K. Bonafede, PhD, MPH, Nimish A. Mohile, MD, Jeffrey A. Bourret, PharmD
Glioblastoma multiforme is the most common malignant primary brain tumor in adults and is associated with poor survival rates. Symptoms often include headaches; nausea and vomiting; and progressive memory, personality, or neurologic deficits. The treatment remains a challenge, and despite the approval of multiple new therapies in the past decade, survival has not improved.
Treatment Decisions in the Management of Malignant Gliomas
Kirk J. Wojno, MD, Frank J. Costa, MD, Robert J. Cornell, MD, Jeffrey D. Small, MD, Erik Pasin, MD, Wim Van Criekinge, PhD, Joseph W. Bigley, MSc, Leander Van Neste, PhD
The diagnosis of prostate cancer is dependent on histologic confirmation in biopsy core tissues. The biopsy procedure is invasive, puts the patient at risk for complications, and is subject to significant sampling errors.
Molecular Tests Can Help to Reduce Repeated Prostate Biopsies
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Results 51 - 60 of 120
Results 51 - 60 of 120