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Diabetes is a chronic disease that affects a staggering 29.1 million in­dividuals in the United States—approximately 9.3% of the population.
There is an urgent unmet need for more effective therapies in pancreatic cancer. The American Cancer Society estimated that approximately 49,000 new cases of pancreatic cancer will be diagnosed in the United States in 2015, and more than 40,500 people will die from this cancer.
Lung cancer is the leading cause of cancer-related mortality in the United States among men and women. The most common type of the disease, non–small-cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases.
The National Cancer Institute estimated that in 2015 there were 73,870 new cases of skin melanoma and more than 9900 patients died from this disease.
Rosacea, a chronic, noncontagious dermatitis of the facial skin, affects approximately 16 million people in the United States.
Breast cancer is one of the most common cancer diagnoses in the United States. The National Cancer Institute estimates that 231,840 American women will be diagnosed with breast cancer, and nearly 40,300 women will die from the disease in 2015.
In this response, Roy and colleagues explain the model’s rationale, noting that its overall objective was to provide a framework for future use.
New Orleans, LA—Those frustrated with low long-term remission rates in adult patients with acute lymphocytic leukemia (ALL) can find hope in the superior outcomes associated with treatment for pediatric ALL. Overall survival (OS) with therapy reaches 85% in children but lags in adults at 45%. Targeting specific pathways and adding novel agents to standard therapy should improve outcomes in adult patients.
Rituximab (Rituxan) maintenance and radioimmunotherapy consolidation after front-line therapy with rituximab have favorable cost-effectiveness in the treatment of follicular lymphoma, found Qiushi Chen, PhD, of the H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, and colleagues.

There is currently no consensus for the management of follicular lymphoma, the most common indolent non-Hodgkin lymphoma, but in current practice, rituximab is the most frequently used front-line therapy. Phase 3 randomized trials have demonstrated that rituximab maintenance and radioimmunotherapy consolidation after front-line rituximab improve progression-free survival (PFS).

New Orleans, LA—The efficiency of rituximab (Rituxan) and the associated cost can be improved by switching from intravenous (IV) to subcutaneous (SC) administration. Such a switch led to a substantial reduction in patient chair time and in active healthcare professional time, said Christof Wiesner, PhD, MPH, of the Market Access Department, Genentech, San Francisco, CA, at the ASH 2013 meeting.
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